Synthesis and Properties of Low-Molecular-Weight PEI-Based Lipopolymers for Delivery of DNA

Rapid enzymatic degradation and fragmentation during DNA administration can result in limited gene expression, and consequently, poor efficacy. It is necessary to use novel vectors for DNA delivery. Herein, we aimed to design useful carriers for enhancing transfection efficiency (TE). These lipopoly...

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Bibliographic Details
Main Authors: Miao-Miao Xun, Zheng Huang, Ya-Ping Xiao, Yan-Hong Liu, Ji Zhang, Ju-Hui Zhang, Xiao-Qi Yu
Format: Article
Language:English
Published: MDPI AG 2018-09-01
Series:Polymers
Subjects:
Online Access:http://www.mdpi.com/2073-4360/10/10/1060