Topological Structure and Robustness of the Lymph Node Conduit System

Summary: Fibroblastic reticular cells (FRCs) form a road-like cellular network in lymph nodes (LNs) that provides essential chemotactic, survival, and regulatory signals for immune cells. While the topological characteristics of the FRC network have been elaborated, the network properties of the mic...

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Bibliographic Details
Main Authors: Mario Novkovic, Lucas Onder, Gennady Bocharov, Burkhard Ludewig
Format: Article
Language:English
Published: Elsevier 2020-01-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124719317279