RIP1 Perturbation Induces Chondrocyte Necroptosis and Promotes Osteoarthritis Pathogenesis via Targeting BMP7

RIP1 Perturbation Induces Chondrocyte Necroptosis and Promotes Osteoarthritis Pathogenesis via Targeting BMP7

Osteoarthritis (OA) is a highly prevalent and debilitating joint disorder that characterized by progressive destruction of articular cartilage. There is no effective disease-modifying therapy for the condition due to limited understanding of the molecular mechanisms on cartilage maintenance and dest...

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Bibliographic Details
Main Authors: Jin Cheng, Xiaoning Duan, Xin Fu, Yanfang Jiang, Peng Yang, Chenxi Cao, Qi Li, Jiying Zhang, Xiaoqing Hu, Xin Zhang, Yingfang Ao
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
cartilage
chondrocyte
osteoarthritis
necroptosis
receptor-interacting protein kinase 1
extracellular matrix
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.638382/full

Internet

https://www.frontiersin.org/articles/10.3389/fcell.2021.638382/full

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