HSP60 knockdown exerts differential response in endothelial cells and monocyte derived macrophages during atherogenic transformation

Abstract Ectopic expression of HSP60 in vascular cells is known to activate auto-immune response that is critical to atherogenic initiation. However, the pathogenic relevance of the aberrant HSP60 upregulation in intracellular signaling pathways associated with atherogenic consequences in vascular c...

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Bibliographic Details
Main Authors: Kavita Shirsath, Apeksha Joshi, Aliasgar Vohra, Ranjitsinh Devkar
Format: Article
Language:English
Published: Nature Publishing Group 2021-01-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-020-79927-2