Evolutionary tradeoffs between economy and effectiveness in biological homeostasis systems.

Biological regulatory systems face a fundamental tradeoff: they must be effective but at the same time also economical. For example, regulatory systems that are designed to repair damage must be effective in reducing damage, but economical in not making too many repair proteins because making excess...

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Bibliographic Details
Main Authors: Pablo Szekely, Hila Sheftel, Avi Mayo, Uri Alon
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS Computational Biology
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23950698/?tool=EBI