Virus/Host Cell Crosstalk in Hypoxic HPV-Positive Cancer Cells

Oncogenic types of human papillomaviruses (HPVs) are major human carcinogens. The expression of the viral E6/E7 oncogenes plays a key role for HPV-linked oncogenesis. It recently has been found that low oxygen concentrations (“hypoxia”), as present in sub-regions of HPV-positive cancers, strongly af...

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Bibliographic Details
Main Authors: Karin Hoppe-Seyler, Julia Mändl, Svenja Adrian, Bianca J. Kuhn, Felix Hoppe-Seyler
Format: Article
Language:English
Published: MDPI AG 2017-07-01
Series:Viruses
Subjects:
Online Access:https://www.mdpi.com/1999-4915/9/7/174