Exploration of Multiple Signaling Pathways Through Which Sodium Tanshinone IIA Sulfonate Attenuates Pathologic Remodeling Experimental Infarction

Exploration of Multiple Signaling Pathways Through Which Sodium Tanshinone IIA Sulfonate Attenuates Pathologic Remodeling Experimental Infarction

The level of maladaptive myocardial remodeling consistently contributes to the poor prognosis of patients following a myocardial infarction (MI). In this study, we investigated whether and how sodium tanshinone IIA sulfonate (STS) would attenuate the post-infarct cardiac remodeling in mice model of...

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Bibliographic Details
Main Authors: Shuai Mao, Matthew Vincent, Maosheng Chen, Minzhou Zhang, Aleksander Hinek
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-07-01
Series:Frontiers in Pharmacology
Subjects:
sodium tanshinone IIA sulfonate
cardiac remodeling
autophagy
apoptosis
AMP kinase pathway
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2019.00779/full

Internet

https://www.frontiersin.org/article/10.3389/fphar.2019.00779/full

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