Sotetsuflavone inhibits proliferation and induces apoptosis of A549 cells through ROS-mediated mitochondrial-dependent pathway

Abstract Background Sotetsuflavone is isolated from Cycas revoluta Thunb., which has biological activity against tumors. However, the anti-proliferative effects of sotetsuflavone on A549 cells and its mechanism are not fully elucidated. Methods This study investigated the mechanisms of growth inhibi...

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Bibliographic Details
Main Authors: Shaohui Wang, Yanlan Hu, Yu Yan, Zhekang Cheng, Tongxiang Liu
Format: Article
Language:English
Published: BMC 2018-08-01
Series:BMC Complementary and Alternative Medicine
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12906-018-2300-z