Phage-mediated dispersal of biofilm and distribution of bacterial virulence genes is induced by quorum sensing.

Phage-mediated dispersal of biofilm and distribution of bacterial virulence genes is induced by quorum sensing.

The microbiome and the phage meta-genome within the human gut are influenced by antibiotic treatments. Identifying a novel mechanism, here we demonstrate that bacteria use the universal communication molecule AI-2 to induce virulence genes and transfer them via phage release. High concentrations (i....

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Bibliographic Details
Main Authors: Friederike S Rossmann, Tomas Racek, Dominique Wobser, Jacek Puchalka, Elaine M Rabener, Matthias Reiger, Antoni P A Hendrickx, Ann-Kristin Diederich, Kirsten Jung, Christoph Klein, Johannes Huebner
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-02-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC4338201?pdf=render

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http://europepmc.org/articles/PMC4338201?pdf=render

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