Inhibition of the C-X-C Motif Chemokine 12 (CXCL12) and Its Receptor CXCR4 Reduces Utero-Placental Expression of the VEGF System and Increases Utero-Placental Autophagy

Inhibition of the C-X-C Motif Chemokine 12 (CXCL12) and Its Receptor CXCR4 Reduces Utero-Placental Expression of the VEGF System and Increases Utero-Placental Autophagy

The placenta, a unique organ that only develops during pregnancy, is essential for nutrient, oxygen, and waste exchange between offspring and mother. Yet, despite its importance, the placenta remains one of the least understood organs and knowledge of early placental formation is particularly limite...

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Bibliographic Details
Main Authors: Ryan L. Ashley, Cheyenne L. Runyan, Marlie M. Maestas, Elisa Trigo, Gail Silver
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-08-01
Series:Frontiers in Veterinary Science
Subjects:
CXCL12
CXCR4
CXCR7
angiogenesis
placenta
MAPK
Online Access:https://www.frontiersin.org/articles/10.3389/fvets.2021.650687/full

Internet

https://www.frontiersin.org/articles/10.3389/fvets.2021.650687/full

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