Concerted Transcriptional Regulation by BRCA1 and COBRA1 in Breast Cancer Cells
<p>Cofactor of BRCA1 (COBRA1) was first identified as a protein that binds to the breast cancer susceptibility gene product BRCA1. COBRA1 modulates estrogen-dependent and independent transcription and suppresses the growth of breast cancer cells. Its expression is significantly reduced in meta...
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Format: | Article |
Language: | English |
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Ivyspring International Publisher
2007-01-01
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Series: | International Journal of Biological Sciences |
Online Access: | http://www.biolsci.org/v03p0486.htm |