A Boolean network of the crosstalk between IGF and Wnt signaling in aging satellite cells.

A Boolean network of the crosstalk between IGF and Wnt signaling in aging satellite cells.

Aging is a complex biological process, which determines the life span of an organism. Insulin-like growth factor (IGF) and Wnt signaling pathways govern the process of aging. Both pathways share common downstream targets that allow competitive crosstalk between these branches. Of note, a shift from...

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Bibliographic Details
Main Authors: Lea Siegle, Julian D Schwab, Silke D Kühlwein, Ludwig Lausser, Stefan Tümpel, Astrid S Pfister, Michael Kühl, Hans A Kestler
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5875862?pdf=render

Internet

http://europepmc.org/articles/PMC5875862?pdf=render

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