Characteristics of changes in the number of yH2AX and Rad51 protein foci in human skin fibroblasts after prolonged exposure to low-dose rate X-ray radiation

Characteristics of changes in the number of yH2AX and Rad51 protein foci in human skin fibroblasts after prolonged exposure to low-dose rate X-ray radiation

Aim: to compare the repair process of DNA double-strand breaks in mammalian cells after acute versus prolonged exposure to X-ray irradiation with different dose rates. Material and methods. Studies were performed on primary human fibroblasts isolated from skin biopsies of healthy volunteers (women,...

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Bibliographic Details
Main Authors: Ozerov I.V., Eremin P.S., Osipov A.N., Eremin I.I., Tsvetkova A.D., Guseva S.S., Ivanova K.Yu., Gavrilenko 0.I., Pustovalova M.V., Smetanina N.M., Grekhova A.K., Lazareva N.L., Pullin A.A., Maksimova О.A., Gordeev A.V., Bushmanov A.Yu., Kotenko K.V.
Format: Article
Language:Russian
Published: Saratov State Medical University 2014-12-01
Series:Саратовский научно-медицинский журнал
Subjects:
Rad51
DNA double-strand breaks
DNA repair
fibroblasts
low dose-rate
X-ray
уН2АХ
Online Access:http://www.ssmj.ru/system/files/2014_04-01_739-743.pdf

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http://www.ssmj.ru/system/files/2014_04-01_739-743.pdf

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