α‐Tocopherol suppresses hepatic steatosis by increasing CPT‐1 expression in a mouse model of diet‐induced nonalcoholic fatty liver disease

α‐Tocopherol suppresses hepatic steatosis by increasing CPT‐1 expression in a mouse model of diet‐induced nonalcoholic fatty liver disease

Abstract Aim Antioxidant therapy for with vitamin E appears to be effective for the treatment of nonalcoholic fatty liver disease　(NAFLD). However, the mechanism of action and optimal therapeutic dosage is unclear. The present study was undertaken to examine whether the effects of α‐tocopherol (α‐To...

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Bibliographic Details
Main Authors: Masanori Tokoro, Koro Gotoh, Yoko Kudo, Yuka Hirashita, Masao Iwao, Mie Arakawa, Mizuki Endo, Junya Oribe, Takayuki Masaki, Koichi Honda, Tetsuya Kakuma, Masataka Seike, Kazunari Murakami, Hirotaka Shibata
Format: Article
Language:English
Published: Wiley 2021-02-01
Series:Obesity Science & Practice
Subjects:
α‐tocopherol
CPT‐1
HepG2 cell
NAFLD model mouse
Online Access:https://doi.org/10.1002/osp4.460

Internet

https://doi.org/10.1002/osp4.460

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