Susceptibility to Aneuploidy in Young Mothers of Down Syndrome Children

We recently observed an increased frequency of binucleated micronucleated lymphocytes in women who had a Down syndrome (DS) child before 35 years of age and the fluorescence in situ hybridization analysis revealed that micronuclei were mainly originating from chromosomal malsegregation events, inclu...

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Bibliographic Details
Main Authors: Lucia Migliore, Francesca Migheli, Fabio Coppedè
Format: Article
Language:English
Published: Hindawi Limited 2009-01-01
Series:The Scientific World Journal
Online Access:http://dx.doi.org/10.1100/tsw.2009.122