Transmission/disequilibrium tests incorporating unaffected offspring.

We propose a new method for family-based tests of association and linkage called transmission/disequilibrium tests incorporating unaffected offspring (TDTU). This new approach, constructed based on transmission/disequilibrium tests for quantitative traits (QTDT), provides a natural extension of the...

Full description

Bibliographic Details
Main Authors: Qinyu Wei, Yuanli Chen, Zheng Zeng, Chang Shu, Lu Long, Jianhua Lu, Yangxin Huang, Ping Yin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4275232?pdf=render