Up-Regulation of Intestinal Phosphate Transporter NaPi-IIb (SLC34A2) by the Kinases SPAK and OSR1

Background/Aims: SPAK (SPS1-related proline/alanine-rich kinase) and OSR1 (oxidative stress-responsive kinase 1), kinases controlled by WNK (with-no-K[Lys] kinase), are powerful regulators of cellular ion transport and blood pressure. Observations in gene-targeted mice disclosed an impact of SPAK/OS...

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Bibliographic Details
Main Authors: Myriam Fezai, Bernat Elvira, Jamshed Warsi, Mossadok Ben-Attia, Zohreh Hosseinzadeh, Florian Lang
Format: Article
Language:English
Published: Karger Publishers 2015-10-01
Series:Kidney & Blood Pressure Research
Subjects:
WNK
Online Access:http://www.karger.com/Article/FullText/368531