Scavenging effect of DOAC-Stop on zifaxaban in vitro and in vivo

Objective To determine the scavenging effect of DOAC-Stop on zifaxaban in plasma. Methods In in vitro experiment, 0.1 mg/mL zifaxaban was added into the plasma derived from Beagle dogs, then, DOAC-Stop with gradient concentration (1/512~1 minitabs) was added to observe the changes of prothrombin tim...

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Bibliographic Details
Main Authors: ZHANG Sipei, ZHANG Yanwen, SUN Shuangyong
Format: Article
Language:zho
Published: Editorial Office of Journal of Third Military Medical University 2021-07-01
Series:Di-san junyi daxue xuebao
Subjects:
Online Access:http://aammt.tmmu.edu.cn/Upload/rhtml/202101080.htm