Deletion of SOCS2 Reduces Post-Colitis Fibrosis via Alteration of the TGFβ Pathway

Deletion of SOCS2 Reduces Post-Colitis Fibrosis via Alteration of the TGFβ Pathway

Inflammatory bowel disease (IBD) is an immunologically mediated chronic intestinal disorder. Growth hormone (GH) administration enhances mucosal repair and decreases intestinal fibrosis in patients with IBD. In the present study, we investigated the effect of cellular sensitivity to GH via suppresso...

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Bibliographic Details
Main Authors: Amna Al-Araimi, Amira Al Kharusi, Asma Bani Oraba, Matar M Al-Maney, Shadia Al Sinawi, Ibrahim Al-Haddabi, Fahad Zadjali
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:International Journal of Molecular Sciences
Subjects:
inflammatory bowel disease
colitis
growth hormone
suppressor of cytokine signaling protein
fibrosis
Online Access:https://www.mdpi.com/1422-0067/21/9/3073

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https://www.mdpi.com/1422-0067/21/9/3073

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