Does Impaired O2 Delivery During Exercise Accentuate Central and Peripheral Fatigue in Patients with Coexistent COPD-CHF?

Does Impaired O2 Delivery During Exercise Accentuate Central and Peripheral Fatigue in Patients with Coexistent COPD-CHF?

Impairment in oxygen (O2) delivery to the central nervous system (brain) and skeletal locomotor muscle during exercise has been associated with central and peripheral neuromuscular fatigue in healthy humans. From a clinical perspective, impaired tissue O2 transport is a key pathophysiological mechan...

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Bibliographic Details
Main Authors: Mayron F. Oliveira, Joel T. J. Zelt, Joshua H. Jones, Daniel M. Hirai, Dennis E. O'Donnell, Samuel eVerges, J. Alberto eNeder
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-01-01
Series:Frontiers in Physiology
Subjects:
Respiratory Muscles
oxygenation
skeletal muscle
chronic obstructive pulmonary disease
chronic heart failure
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphys.2014.00514/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fphys.2014.00514/full

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