PolyI:C Upregulated CCR5 and Promoted THP-1-Derived Macrophage Chemotaxis via TLR3/JMJD1A Signalling
Objective: This study aimed to evaluate the specific roles of polyinosinic:polycytidylic acid (polyI:C) in macrophage chemotaxis and reveal the potential regulatory mechanisms related to chemokine receptor 5 (CCR5). Materials and Methods: In this experimental study, THP-1-derived macrophages (THP1...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
Royan Institute (ACECR), Tehran
2020-10-01
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Series: | Cell Journal |
Subjects: | |
Online Access: | https://celljournal.org/journal/article/abstract/6713 |