Global Conservation of Protein Status between Cell Lines and Xenografts

Common preclinical models for testing anticancer treatment include cultured human tumor cell lines in monolayer, and xenografts derived from these cell lines in immunodeficient mice. Our goal was to determine how similar the xenografts are compared with their original cell line and to determine whet...

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Bibliographic Details
Main Authors: Julian Biau, Emmanuel Chautard, Frank Court, Bruno Pereira, Pierre Verrelle, Flavien Devun, Leanne De Koning, Marie Dutreix
Format: Article
Language:English
Published: Elsevier 2016-08-01
Series:Translational Oncology
Online Access:http://www.sciencedirect.com/science/article/pii/S1936523316300444