Flow of cerebrospinal fluid is driven by arterial pulsations and is reduced in hypertension

Flow of cerebrospinal fluid is driven by arterial pulsations and is reduced in hypertension

Arterial pulsations are thought to drive CSF flow through perivascular spaces (PVSs), but this has never been quantitatively shown. Using particle tracking to quantify CSF flow velocities in PVSs of live mice, the authors show that flow speeds match the instantaneous speeds of the pulsing artery wal...

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Bibliographic Details
Main Authors: Humberto Mestre, Jeffrey Tithof, Ting Du, Wei Song, Weiguo Peng, Amanda M. Sweeney, Genaro Olveda, John H. Thomas, Maiken Nedergaard, Douglas H. Kelley
Format: Article
Language:English
Published: Nature Publishing Group 2018-11-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-018-07318-3

Internet

https://doi.org/10.1038/s41467-018-07318-3

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