Semi-Automatic Signature-Based Segmentation Method for Quantification of Neuromelanin in Substantia Nigra

In Parkinson’s disease (PD), there is a reduction of neuromelanin (NM) in the substantia nigra (SN). Manual quantification of the NM volume in the SN is unpractical and time-consuming; therefore, we aimed to quantify NM in the SN with a novel semi-automatic segmentation method. Twenty pati...

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Bibliographic Details
Main Authors: Gašper Zupan, Dušan Šuput, Zvezdan Pirtošek, Andrej Vovk
Format: Article
Language:English
Published: MDPI AG 2019-11-01
Series:Brain Sciences
Subjects:
Online Access:https://www.mdpi.com/2076-3425/9/12/335