New antagonist agents of neuropeptide y receptors

New antagonist agents of neuropeptide y receptors

In the CNS, NPY has been implicated in obesity and feeding, endocrine function and metabolism. Potent and selective rNPY antagonists will be able to probe the merits of this approach for the treatment of obesity. We report the synthesis and preliminary evaluation of some hydrazide derivatives as ant...

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Bibliographic Details
Main Authors: Ignacio Aldana, Isabel Rivero, Argimiro Rivero, Patricio Huenchuñir, Carmen Frigola, Maria Luisa Alonso, Antonio Monge, D. H. Caignard, P. Renard
Format: Article
Language:English
Published: Sociedade Brasileira de Química 2000-12-01
Series:Química Nova
Subjects:
obesity
energy metabolism
weight reduction
neuropeptide Y
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422000000600005

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422000000600005

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