Identification of Autoreactive B Cell Subpopulations in Peripheral Blood of Autoimmune Patients With Pemphigus Vulgaris

Identification of Autoreactive B Cell Subpopulations in Peripheral Blood of Autoimmune Patients With Pemphigus Vulgaris

Pemphigus vulgaris (PV) is a rare blistering disease caused by IgG autoantibodies against the epidermal adhesion molecules desmoglein (Dsg)3 and Dsg1 providing a well-characterized paradigm of an antibody-mediated organ-specific autoimmune disease. In PV patients who have achieved clinical remission...

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Bibliographic Details
Main Authors: Robert Pollmann, Elias Walter, Thomas Schmidt, Jens Waschke, Michael Hertl, Christian Möbs, Rüdiger Eming
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-06-01
Series:Frontiers in Immunology
Subjects:
autoimmunity
pemphigus vulgaris
desmoglein 3
B cells
flow cytometry
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.01375/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.01375/full

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