Prenatally traumatized mice reveal hippocampal methylation and expression changes of the stress-related genes Crhr1 and Fkbp5

Abstract In our previous study, we found that prenatal trauma exposure leads to an anxiety phenotype in mouse pups, characterized by increased corticosterone levels and increased anxiety-like behavior. In order to understand the mechanisms by which aversive in utero experience leads to these long-la...

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Bibliographic Details
Main Authors: Anne-Christine Plank, Stefan Frey, Lukas Andreas Basedow, Jalal Solati, Fabio Canneva, Stephan von Hörsten, Oliver Kratz, Gunther H. Moll, Yulia Golub
Format: Article
Language:English
Published: Nature Publishing Group 2021-03-01
Series:Translational Psychiatry
Online Access:https://doi.org/10.1038/s41398-021-01293-y