Expression weighted cell type enrichments reveal genetic and cellular nature of major brain disorders
The cell types that trigger the primary pathology in many brain diseases remain largely unknown. One route to understanding the primary pathological cell type for a particular disease is to identify the cells expressing susceptibility genes. Although this is straightforward for monogenic conditions...
Main Authors: | Nathan Gerald Skene, Seth G N Grant |
---|---|
Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2016-01-01
|
Series: | Frontiers in Neuroscience |
Subjects: | |
Online Access: | http://journal.frontiersin.org/Journal/10.3389/fnins.2016.00016/full |
Similar Items
-
Mid-gestational exposure to histone deacetylase inhibitor suberoylanilide hydroxamic acid influence cortical interneuron and astrocyte in mouse brain
by: Nunung Yuniarti, et al.
Published: (2017-06-01) -
Dual Roles of Astrocyte-Derived Factors in Regulation of Blood-Brain Barrier Function after Brain Damage
by: Shotaro Michinaga, et al.
Published: (2019-01-01) -
Characterization of a Primate Blood-Brain Barrier Co-Culture Model Prepared from Primary Brain Endothelial Cells, Pericytes and Astrocytes
by: Daisuke Watanabe, et al.
Published: (2021-09-01) -
Molecular and Cellular Mechanisms of Reelin Signaling in the Adult Hippocampus
by: Trotter, Justin Howard
Published: (2013) -
Laundering CNV data for candidate process prioritization in brain disorders
by: Maria A. Zelenova, et al.
Published: (2019-12-01)