Isoniazid-Induced Severe Hepatotoxicity: An Infrequent but Preventable Cause of Liver Failure in Children Treated for Latent Tuberculosis Infection

Isoniazid (INH) monotherapy has gained widespread acceptance as an efficacious therapy for latent tuberculosis infection (LTBI) especially in low-prevalence settings. Although INH related hepatotoxicity is well recognized, progression to severe liver dysfunction requiring care at a transplant center...

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Bibliographic Details
Main Authors: Dan Desrochers, Regino P. González-Peralta, Daniel T. McClenathan, Michael J. Wilsey, Allah Haafiz
Format: Article
Language:English
Published: SAGE Publishing 2011-01-01
Series:Clinical Medicine Insights: Pediatrics
Online Access:https://doi.org/10.4137/CMPed.S6406