Segmenting the Human Genome into Isochores

The human genome is a mosaic of isochores, which are long (>200 kb) DNA sequences that are fairly homogeneous in base composition and can be assigned to five families comprising 33%–59% of GC composition. Although the compartmentalized organization of the mammalian genome has been investigated fo...

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Bibliographic Details
Main Authors: Paolo Cozzi, Luciano Milanesi, Giorgio Bernardi
Format: Article
Language:English
Published: SAGE Publishing 2015-01-01
Series:Evolutionary Bioinformatics
Online Access:https://doi.org/10.4137/EBO.S27693