Iron deposition following chronic myocardial infarction as a substrate for cardiac electrical anomalies: initial findings in a canine model.

Iron deposition has been shown to occur following myocardial infarction (MI). We investigated whether such focal iron deposition within chronic MI lead to electrical anomalies.Two groups of dogs (ex-vivo (n = 12) and in-vivo (n = 10)) were studied at 16 weeks post MI. Hearts of animals from ex-vivo...

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Main Authors: Ivan Cokic, Avinash Kali, Xunzhang Wang, Hsin-Jung Yang, Richard L Q Tang, Anees Thajudeen, Michael Shehata, Allen M Amorn, Enzhao Liu, Brian Stewart, Nathan Bennett, Doron Harlev, Sotirios A Tsaftaris, Warren M Jackman, Sumeet S Chugh, Rohan Dharmakumar
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3774668?pdf=render