Profiles of 14-3-3 and Total Tau in CSF Samples of Chinese Patients of Different Genetic Prion Diseases

Profiles of 14-3-3 and Total Tau in CSF Samples of Chinese Patients of Different Genetic Prion Diseases

BackgroundThe abnormal alterations of proteins 14-3-3 and tau in cerebrospinal fluid (CSF) are widely used for the diagnosis of sporadic Creutzfeldt-Jakob disease (sCJD), while the situations of CSF biomarkers in genetic prion diseases (gPrDs), particularly in Chinese gPrDs patients, have not been w...

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Bibliographic Details
Main Authors: Cao Chen, Chao Hu, Qi Shi, Wei Zhou, Kang Xiao, Yuan Wang, Lian Liu, Jia Chen, Ying Xia, Xiao-Ping Dong
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-09-01
Series:Frontiers in Neuroscience
Subjects:
prion
genetic prion disease
CSF
14-3-3
tau
Online Access:https://www.frontiersin.org/article/10.3389/fnins.2019.00934/full

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https://www.frontiersin.org/article/10.3389/fnins.2019.00934/full

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