M1 Macrophage and M1/M2 ratio defined by transcriptomic signatures resemble only part of their conventional clinical characteristics in breast cancer

M1 Macrophage and M1/M2 ratio defined by transcriptomic signatures resemble only part of their conventional clinical characteristics in breast cancer

Abstract Tumor associated macrophages (TAMs) play a critical role in biology of various cancers, including breast cancer. In the current study, we defined “M1” macrophage and “M1”/“M2” ratio by transcriptomic signatures using xCell. We investigated the association between high level of “M1” macropha...

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Bibliographic Details
Main Authors: Masanori Oshi, Yoshihisa Tokumaru, Mariko Asaoka, Li Yan, Vikas Satyananda, Ryusei Matsuyama, Nobuhisa Matsuhashi, Manabu Futamura, Takashi Ishikawa, Kazuhiro Yoshida, Itaru Endo, Kazuaki Takabe
Format: Article
Language:English
Published: Nature Publishing Group 2020-10-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-020-73624-w

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https://doi.org/10.1038/s41598-020-73624-w

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