1,25-dihydroxyvitamin D3 induces LL-37 and HBD-2 production in keratinocytes from diabetic foot ulcers promoting wound healing: an in vitro model.

Diabetic foot ulcers (DFU) are one of the most common diabetes-related cause of hospitalization and often lead to severe infections and poor healing. It has been recently reported that patients with DFU have lower levels of antimicrobial peptides (AMPs) at the lesion area, which contributes with the...

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Main Authors: Irma Gonzalez-Curiel, Valentin Trujillo, Alejandra Montoya-Rosales, Kublai Rincon, Bruno Rivas-Calderon, Jeny deHaro-Acosta, Paulina Marin-Luevano, Daniel Lozano-Lopez, Jose A Enciso-Moreno, Bruno Rivas-Santiago
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4206472?pdf=render