Ocrelizumab: a new milestone in multiple sclerosis therapy
B cells play a central role in the pathogenesis of multiple sclerosis (MS): they are involved in the activation of pro-inflammatory T cells, secretion of pro-inflammatory cytokines and production of autoantibodies directed against myelin. Hence, the use of B cell-depleting monoclonal antibodies as t...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
SAGE Publishing
2018-05-01
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Series: | Therapeutic Advances in Neurological Disorders |
Online Access: | https://doi.org/10.1177/1756286418773025 |