In Vivo Efficacy of a Cocktail of Human Monoclonal Antibodies (CL184) Against Diverse North American Bat Rabies Virus Variants

In Vivo Efficacy of a Cocktail of Human Monoclonal Antibodies (CL184) Against Diverse North American Bat Rabies Virus Variants

Following rabies virus (RABV) exposure, a combination of thorough wound washing, multiple-dose vaccine administration and the local infiltration of rabies immune globulin (RIG) are essential components of modern post-exposure prophylaxis (PEP). Although modern cell-culture-based rabies vaccines are...

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Bibliographic Details
Main Authors: Richard Franka, William C. Carson, James A. Ellison, Steven T. Taylor, Todd G. Smith, Natalia A. Kuzmina, Ivan V. Kuzmin, Wilfred E. Marissen, Charles E. Rupprecht
Format: Article
Language:English
Published: MDPI AG 2017-09-01
Series:Tropical Medicine and Infectious Disease
Subjects:
bat viral diseases
monoclonal antibody
immune globulin
lyssavirus
post-exposure prophylaxis
rabies
vaccine
zoonosis
Online Access:https://www.mdpi.com/2414-6366/2/3/48

Internet

https://www.mdpi.com/2414-6366/2/3/48

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