Neural stem cells as a novel platform for tumor-specific delivery of therapeutic antibodies.

Neural stem cells as a novel platform for tumor-specific delivery of therapeutic antibodies.

BACKGROUND: Recombinant monoclonal antibodies have emerged as important tools for cancer therapy. Despite the promise shown by antibody-based therapies, the large molecular size of antibodies limits their ability to efficiently penetrate solid tumors and precludes efficient crossing of the blood-bra...

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Bibliographic Details
Main Authors: Richard T Frank, Marissa Edmiston, Stephen E Kendall, Joseph Najbauer, Chia-Wei Cheung, Thewodros Kassa, Marianne Z Metz, Seung U Kim, Carlotta A Glackin, Anna M Wu, Paul J Yazaki, Karen S Aboody
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2789379?pdf=render

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http://europepmc.org/articles/PMC2789379?pdf=render

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