Preclinical In Vitro Studies with 3D Spheroids to Evaluate Cu(DDC)<sub>2</sub> Containing Liposomes for the Treatment of Neuroblastoma

Preclinical in vitro studies of drug candidates for anticancer therapy are generally conducted on well-established 2D cell models. Unfortunately, these models are unable to mimic the properties of in vivo tumors. However, in vitro 3D models (spheroids) have been proven to be superior in reflecting t...

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Bibliographic Details
Main Authors: Friederike Hartwig, Monika Köll-Weber, Regine Süss
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Pharmaceutics
Subjects:
Online Access:https://www.mdpi.com/1999-4923/13/6/894