Regulation of CP-25 on P-glycoprotein in synoviocytes of rats with adjuvant arthritis

Objective: Methotrexate (MTX) is a commonly used drug for the treatment of rheumatoid arthritis (RA) and it has been studied in RA resistance recently. P-glycoprotein (P-gp) is one of the important transporters that mediate MTX resistance. This study investigated the effect of Paeoniflorin-6′-O-benz...

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Bibliographic Details
Main Authors: Hao Tang, Yi-jin Wu, Feng Xiao, Bin Wang, James Asenso, Yong Wang, Wei Sun, Chun Wang, Wei Wei
Format: Article
Language:English
Published: Elsevier 2019-11-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332219334845