Downregulated miR-98-5p promotes PDAC proliferation and metastasis by reversely regulating MAP4K4

Downregulated miR-98-5p promotes PDAC proliferation and metastasis by reversely regulating MAP4K4

Abstract Background The aberrant expression of microRNAs (miRNAs) has emerged as important hallmarks of cancer. However, the molecular mechanisms underlying the differences of miRNA expression remain unclear. Many studies have reported that miR-98-5p plays vital functions in the development and prog...

Full description

Bibliographic Details
Main Authors: Yue Fu, Xinchun Liu, Qiuyang Chen, Tongtai Liu, Cheng Lu, Jun Yu, Yi Miao, Jishu Wei
Format: Article
Language:English
Published: BMC 2018-07-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
MiR-98-5p
MAP4K4
Proliferation
Migration
Invasion
MAPK/ERK signaling pathway
Online Access:http://link.springer.com/article/10.1186/s13046-018-0807-2

Internet

http://link.springer.com/article/10.1186/s13046-018-0807-2

Similar Items