The Protective Effects of Salidroside from Exhaustive Exercise-Induced Heart Injury by Enhancing the PGC-1α–NRF1/NRF2 Pathway and Mitochondrial Respiratory Function in Rats

Objective. To test the hypothesis that salidroside (SAL) can protect heart from exhaustive exercise-induced injury by enhancing mitochondrial respiratory function and mitochondrial biogenesis key signaling pathway PGC-1α–NRF1/NRF2 in rats. Methods. Male Sprague-Dawley rats were divided into 4 groups...

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Bibliographic Details
Main Authors: Zheng Ping, Long-fei Zhang, Yu-juan Cui, Yu-mei Chang, Cai-wu Jiang, Zhen-zhi Meng, Peng Xu, Hai-yan Liu, Dong-ying Wang, Xue-bin Cao
Format: Article
Language:English
Published: Hindawi Limited 2015-01-01
Series:Oxidative Medicine and Cellular Longevity
Online Access:http://dx.doi.org/10.1155/2015/876825