DNA methylation changes in ovarian cancer are cumulative with disease progression and identify tumor stage

<p>Abstract</p> <p>Background</p> <p>Hypermethylation of promoter CpG islands with associated loss of gene expression, and hypomethylation of CpG-rich repetitive elements that may destabilize the genome are common events in most, if not all, epithelial cancers.</p>...

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Bibliographic Details
Main Authors: DeGeest Koen, Holtan Nicholas, Futscher Bernard W, Watts George S, Domann Frederick E, Rose Stephen L
Format: Article
Language:English
Published: BMC 2008-09-01
Series:BMC Medical Genomics
Online Access:http://www.biomedcentral.com/1755-8794/1/47