Activation of Sterol Regulatory Element Binding Factors by Fenofibrate and Gemfibrozil Stimulate Myelination in Zebrafish

Activation of Sterol Regulatory Element Binding Factors by Fenofibrate and Gemfibrozil Stimulate Myelination in Zebrafish

Oligodendrocytes are major myelin-producing cells and play essential roles in the function of a healthy nervous system. However, they are also one of the most vulnerable neural cell types in the central nervous system (CNS), and myelin abnormalities in the CNS are found in a wide variety of neurolog...

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Bibliographic Details
Main Authors: Yuhei Nishimura, Yoshifumi Ashikawa, Shiko Okabe, Shota Sasagawa, Soichiro Murakami, Mizuki Yuge, Koki Kawaguchi, Reiko Kawase, TOSHIO TANAKA
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-07-01
Series:Frontiers in Pharmacology
Subjects:
Fenofibrate
Gemfibrozil
Zebrafish
comparative transcriptomics
Myelination
oligodendrocytes
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphar.2016.00206/full

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http://journal.frontiersin.org/Journal/10.3389/fphar.2016.00206/full

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