Screening for Genetic Mutations for the Early Diagnosis of Common Variable Immunodeficiency in Children With Refractory Immune Thrombocytopenia: A Retrospective Data Analysis From a Tertiary Children's Center

Screening for Genetic Mutations for the Early Diagnosis of Common Variable Immunodeficiency in Children With Refractory Immune Thrombocytopenia: A Retrospective Data Analysis From a Tertiary Children's Center

Aim: This study aimed to identify common variable immunodeficiency (CVID) by high-throughput next-generation sequencing (NGS) in children with refractory immune thrombocytopenia (RITP) to facilitate early diagnosis.Methods: CVID-related genetic mutations were explored in patients with RITP during 20...

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Bibliographic Details
Main Authors: Jingyao Ma, Lingling Fu, Hao Gu, Zhenping Chen, Jialu Zhang, Shasha Zhao, Xiaojing Zhu, Huiqing Liu, Runhui Wu
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-12-01
Series:Frontiers in Pediatrics
Subjects:
children
common variable immunodeficiency
next-generation sequencing
refractory immune thrombocytopenia
mutation
Online Access:https://www.frontiersin.org/articles/10.3389/fped.2020.595135/full

Internet

https://www.frontiersin.org/articles/10.3389/fped.2020.595135/full

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