GDH-Dependent Glutamate Oxidation in the Brain Dictates Peripheral Energy Substrate Distribution

GDH-Dependent Glutamate Oxidation in the Brain Dictates Peripheral Energy Substrate Distribution

Glucose, the main energy substrate used in the CNS, is continuously supplied by the periphery. Glutamate, the major excitatory neurotransmitter, is foreseen as a complementary energy contributor in the brain. In particular, astrocytes actively take up glutamate and may use it through oxidative gluta...

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Bibliographic Details
Main Authors: Melis Karaca, Francesca Frigerio, Stephanie Migrenne, Juliette Martin-Levilain, Dorte M. Skytt, Kamilla Pajecka, Rafael Martin-del-Rio, Rolf Gruetter, Jorge Tamarit-Rodriguez, Helle S. Waagepetersen, Christophe Magnan, Pierre Maechler
Format: Article
Language:English
Published: Elsevier 2015-10-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124715010141

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http://www.sciencedirect.com/science/article/pii/S2211124715010141

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