Microtubule Hyperacetylation Enhances KL1-Dependent Micronucleation under a Tau Deficiency in Mammary Epithelial Cells

Microtubule Hyperacetylation Enhances KL1-Dependent Micronucleation under a Tau Deficiency in Mammary Epithelial Cells

Enhanced microtubule acetylation has been identified as a negative prognostic indicator in breast cancer. We reported previously that primary cultured human mammary epithelial cells manifest breast cancer-related aneuploidization via the activation of severing protein katanin-like (KL)1 when tau is...

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Bibliographic Details
Main Author: Haruka Sudo
Format: Article
Language:English
Published: MDPI AG 2018-08-01
Series:International Journal of Molecular Sciences
Subjects:
breast cancer
microtubule acetylation
microtubule severing
mitotic spindle
tau
Online Access:http://www.mdpi.com/1422-0067/19/9/2488

Internet

http://www.mdpi.com/1422-0067/19/9/2488

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