The Dual-Role of Methylglyoxal in Tumor Progression – Novel Therapeutic Approaches

One of the hallmarks of cancer cells is their metabolic reprogramming, which includes the preference for the use of anaerobic glycolysis to produce energy, even in presence of normal oxygen levels. This phenomenon, known as “Warburg effect”, leads to the increased production of reactive intermediate...

Full description

Bibliographic Details
Main Authors: Alessia Leone, Cecilia Nigro, Antonella Nicolò, Immacolata Prevenzano, Pietro Formisano, Francesco Beguinot, Claudia Miele
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Oncology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.645686/full