Growth Factor Dependent Regulation of Centrosome Function and Genomic Instability by HuR

The mRNA binding protein HuR is over expressed in cancer cells and contributes to disease progression through post-transcriptional regulation of mRNA. The regulation of HuR and how this relates to glioma is the focus of this report. SRC and c-Abl kinases regulate HuR sub-cellular trafficking and inf...

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Bibliographic Details
Main Authors: Natalia Filippova, Xiuhua Yang, Louis Burt Nabors
Format: Article
Language:English
Published: MDPI AG 2015-03-01
Series:Biomolecules
Subjects:
Src
Online Access:http://www.mdpi.com/2218-273X/5/1/263