Comparing serum protein levels can aid in differentiating HPV-negative and -positive oropharyngeal squamous cell carcinoma patients.

Comparing serum protein levels can aid in differentiating HPV-negative and -positive oropharyngeal squamous cell carcinoma patients.

<h4>Background</h4>The surrogate immunohistochemical marker, p16INK4a, is used in clinical practice to determine the high-risk human papillomavirus (HPV) status of oropharyngeal squamous cell carcinomas (OPSCC). With a specificity of 83%, this will misclassify some patients compared with...

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Main Authors: Amy Dickinson, Mayank Saraswat, Stina Syrjänen, Tiialotta Tohmola, Robert Silén, Reija Randén-Brady, Timo Carpén, Jaana Hagström, Caj Haglund, Petri Mattila, Antti Mäkitie, Sakari Joenväärä, Suvi Silén
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0233974

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https://doi.org/10.1371/journal.pone.0233974

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