Dual drugs release from nanoporously bioactive coating on polyetheretherketone for enhancement of antibacterial activity, rBMSCs responses and osseointegration

A bioactive coating of nanoporous magnesium calcium silicate (n-MCS) on polyetheretherketone (ncPK) surface was prepared, and dual drugs of genistein (GS) and curcumin (CR) were co-loaded into coating of ncPK (dncPK). The results revealed that compared with polyetheretherketone (PEEK), surface rough...

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Bibliographic Details
Main Authors: Fei Zou, Feizhou Lv, Xiaosheng Ma, Xinlei Xia, Liang Cai, Shiqi Mei, Jie Wei, Yunfei Niu, Jianyuan Jiang
Format: Article
Language:English
Published: Elsevier 2020-03-01
Series:Materials & Design
Online Access:http://www.sciencedirect.com/science/article/pii/S0264127519308718